Running Multiple Instances of Async PRAW
Async PRAW performs rate limiting dynamically based on the HTTP response headers from Reddit. As a result you can safely run a handful of Async PRAW instances without any additional configuration.
Running more than a dozen or so instances of Async PRAW concurrently may occasionally result in exceeding Reddit’s rate limits as each instance can only guess how many other instances are running.
If you are authorized on other users’ behalf, each authorization should have its own rate limit, even when running from a single IP address.
The recommended way to run multiple instances of Async PRAW is to simply write separate independent Python programs. With this approach one program can monitor a comment stream and reply as needed, and another program can monitor a submission stream, for example.
If these programs need to share data consider using a third-party system such as a database or queuing system.